Many places where cancer is common are positioned nearВ plants or factories that produce harmful chemicals, but other areas are desolate and isolated. While researches sometimes uncover a lack of corporate oversight, the scientific community still has aВ limited understanding of cancer itself.В This means,В despite the myriad theories about what causes cancer, causes often remain ambiguous especially due toВ the lack of common factors betweenВ clusters. How do cancer clusters form? Unfortunately, investigations rarely lead to a clearer understanding of what causes cancer in certain areas. Given different places so frequently have radically different cancer rates, the outbreaks below have been subject to a heavy amount of research, investigation, and public scrutiny. Clear cell kidney cancer is genetically noted for the biallelic inactivation of VHL tumor suppressor, which leads to the stabilization and accumulation of HIFs (37, 50, 54). Current cancer clusters are breaking out everywhere from small Canadian towns to booming cities like San Francisco. Kidney cancerderived mTOR-activating mutants are resistant to REDD1-mediated inhibition and promote rapamycin-sensitive tumor formation in vivo. SomeВ cancer clusters have possible causes, although investigating and discovering thoseВ causes can take years. Spikes in cancer, or cancer clusters, occur when a high number of people in a small geographical area experience similar ailments over a short period of time. According to the National Cancer Institute, a cancer cluster is the occurrence of a greater than expected number of cancer cases among a group of people in a defined geographic area over a specific time period.

Cancer clusters